SINGLASIK
SINGLASIK Centre
Singapore National Eye Centre
11 Third Hospital Avenue Singapore 168751
Tel: +65 6227 7266 (Appointments)
+65 6322 8891 (Enquiries)
Sms: +65 9725 2366
Fax: +65 6226 3403
Email: singlasik@snec.com.sg
Website: www.singlasik.com.sg

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our doctors - CV
Name: Professor Donald Tan
Senior Consultant and Head, Corneal Service, SNEC
Director, Singapore Eye Research Institute
Medical Director, Singapore Eye Bank
Head, Dept of Ophthalmology, National University of Singapore
Professional Qualifications
  • M.B.B.S. (Singapore) (1983)
  • F.R.C.S. (Glasgow) (1988)
  • F.R.C.Ophth (U.K.) (1989)
  • F.A.M.S. (1994)
  • F.R.C.S. (Edinburgh) (1998)
Professional Appointments & Memberships
  • Medical Director, Singapore National Eye Centre
  • Senior Consultant & Head, Corneal Service, Singapore National Eye Centre
  • Chairman, Singapore Eye Research Institute
  • Medical Director, Singapore Eye Bank
  • Head, Dept of Ophthalmology, National University of Singapore
  • Professor of Ophthalmology, Yong Loo Lin School of Medicine , National University of Singapore
  • Senior Consultant, Dept of Ophthalmology, National University Hospital
  • Council member, National Medical Research Council
  • Member, Ministry of Health Advisory Committee on Transplantation
  • Member, Expert Panel for Ophthalmology, Health Science Authority
  • Board Member, The Cornea Society
  • Member, Scientific Advisory Board, Bausch & Lomb
  • Member, Ocular Surgery News Europe/Asia-Pacific Edition Editorial Board
  • Chairman, Scientific Advisory Board, NeuroVision, Inc.
  • Country Liaison, Tear Film & Ocular Surface Society
  • President, Asia Cornea Society
  • Board Member, Asia Cornea Foundation
  • Board Member, Asia-Pacific Contact Lens Association of Ophthalmologists
  • Member, Asia Pacific Society of Eye Genetics
  • Scientific Expert Adviser, Tianjin Eye Center of the Tianjin Medical University
  • Member, Asia Pacific Dry Eye Advisory Board
Awards & Accolades
  • 1997 Pacific Academy of Ophthamology Distinguished Service Award
  • 2001 Asia-Pacific Academy of Ophthalmology De Ocampo Award
  • 2004 American Society of Cataract and Refractive Surgery (ASCRS) 2004 Annual
  • Meeting Film Festival Best Teaching Video Award
  • 2004 American Society of Cataract and Refractive Surgery (ASCRS) 2004 Annual Meeting Best Scientific Presentation Award: Keratoplasty Session
  • 2005 American Society of Cataract and Refractive Surgery (ASCRS) 2005 Annual Meeting Film Festival Award (First Prize)
  • 2006 American Society of Cataract and Refractive Surgery (ASCRS) 2006 Annual Meeting Best Scientific Presentation Award: Cornea Session
  • 2006 Minister For Health Award: For Outstanding Performance In Public Health – Outbreak of Fusarium Keratitis
  • 2006 American Academy of Ophthalmology Distinguished Achievement Award
  • 2007 American Academy of Ophthalmology (AAO) Meeting Best Paper Award
  • 2008 National Outstanding Clinician Scientist Award - awarded by National Medical Research Council, Ministry of Health, Singapore
  • 2008 American Society of Cataract and Refractive Surgery (ASCRS) 2008 Annual Meeting Film Festival Award (First Prize)

Selected Publications, Research Interest & Trials

Corneal transplantation, artificial cornea surgery, ocular surface stem cell culture and transplantation, corneal refractive surgery, myopia

Selected Publications, Research Interest & Trials

Publications:

  1. Donald TH Tan, Prathiba Janardhanan, Huijun Zhou, Yiong-Huak Chan, Hla Myint Htoon, Leonard PK Ang, Laurence S Lim Penetrating Keratoplasty in Asian Eyes - The Singapore Corneal Transplant Study. Am J Ophthalmology 2008 June (Vol 115, No. 6): 975-982
  2. Yong M Por, Jacob Y Chuan Cheng, Anand Parthasarathy, Jodhbir S Mehta, Donald TH Tan Outcomes of Femtosecond Laser-Assisted Penetrating Keratoplasty. Am J Ophthalmology 2008 May (Vol 145, No. 5): 772-774
  3. Anshu Arundhati, Brendon Zhou Hui Jun, Prathiba Janardhan, Donald TH Tan Iris Reconstruction in penetrating keratoplasty Surgical techniques and a case-control study to valuate effect on graft survival. Am J Ophthalmol. 2008 Feb;145(2):203-209
  4. Laurence S. Lim, Han T. Aung, Tin Aung, Donald TH Tan Corneal Imaginign with Anterior Segment Optical Coherence Tomography for Lamellar Keratoplasty Procedures. Am J Opthalmology (Vol. 145, No. 1)[Jan], 81-90. 2008
  5. Mehta, J.S, Por YM, Beuerman R, Tan D.T.H. Glide Insertion Technique for Donor Cornea Lenticule during Descemets Stripping Automated Endothelial Keratoplasty. Journal of Cataract Refractive Surgery. 2007 Nov;33(11):1846-50
  6. Tan D.T.H, Mehta J.S. Future Directions in Lamellar Corneal Transplantation. Cornea (Vol 26, Suppl. 1)[Oct], S21-S28. 2007
  7. Parthasarathy A, Por Y.M. Tan D.T.H. Use of a “small bubble technique” to increase the success of Anwar’s “big-bubble technique” for deep lamellar keratoplasty with complete baring of Descemet’s membrane British Journal of Ophthalmology 2007 Oct; 91(10): 1369-73.
  8. Parthasarathy A, Theng J, Ti S.E., Tan D.T.H . Infectious keratitis after Laser Epithelial Keratomileusis. Journal of Refractive Surgery. 2007 Oct; 23(8):832-5
  9. Parthasarathy A, Tan D.T.H. Deep Lamellar Keratoplasty for Acanthamoeba Keratitis. Cornea (Vol 26, No. 8)[Sept], 1021-1023. 2007
  10. Susiyanti M, Mehta J.S, Tan D.T.H . Bilateral Deep anterior Lamellar Keratoplasty for the management of Bilateral Post-LASIK Mycobacterial Keratitis. Journal Cataract Refractive Surgery. 2007 Sep;33(9):1641-3
  11. Mehta J.S, Por Y.M, Cajucom-Uy H, Parthasarathy A, Tan D.T.H . FemtosecondLaser for Endothelial Keratoplasty. Journal Cataract Refractive Surgery. 2007 Jul;33(7):1141; author reply 1141-2
  12. Li SH, Li J, Tan D.T.H., Beuerman R.W . Expression and Function of Muscarinic Receptor Subtypes on Human Cornea and Conjunctiva. Investigative Ophthalmology & Vision Science. 2007 Jul;48(7):2987-96.
  13. Ti SE, Scott J.A., Janardhanan P., Tan D.T.H. Therapeutic keratoplasty for advanced suppurative keratitis. Am J Ophthalmology (Vol. 143, No. 5)[May], 755-762. 2007
  14. Tay A.B.G, Tan D.T.H, Lye K.W, Theng J., Parthasarathy A., Por Y.M. Osteo-odonto-keratoprosthesis surgery: a combined ocular-oral procedure for ocular blindness A.(Int J Oral Maxillofac. Surg), Sep 2007. 36(9):807-13 Epub 2007 Jul 13
  15. Parthasarathy A , Mehta JS, Ming PY, Cajucom-Uy H, Tan DT. The use of the femtosecond laser in penetrating keratoplasty. Am J Ophthalmol. 2007 May;143(5):737-742.
  16. Liu S.H, Li J., Tan D.T.H., Beuerman R.W. The Eyelid Margin: A Transitional Zone for Two Eithelial Phenotypes. 2006. Archives of Ophthalmology, April 2007. 125: 523-532
  17. Tan DT. Ang LP. Modified automated lamellar therapeutic keratoplasty for keratoconus: a new technique. Cornea. 2006 Dec;25(10):1217-9
  18. Ang L.P.K, Cheng Z.Y., Beuerman R.W., Teoh S.H., Zhu X., Tan D.T.H. The development of a serum-free derived bioengineered conjunctival epithelial equivalent using an ultrathin poly(epsilon-caprolactone) membrane substrate. Invest Ophthalmol Vis Sci 2006; 47(1): 105 – 112
  19. Chua W.H., Balakrishnan V., Chan Y.H. Tong L., Ling Y., Quah B.L., Tan D.T.H. Atropine for the treatment of childhood myopia. Ophthalmology 2006 Dec ;113(12) :2285-2291
  20. Khor W.B, Aung T., Saw S.M., Wong T.Y., Tambyah P.A., Tan A.L., Beuerman R.W., Lim L., Chan W.K., Heng W.J., Lim J., Loh R.S., Lee S.B., Tan D.T.H . An outbreak of Fusarium keratitis associated with contact lens wear in Singapore. JAMA 2006; 295(24):2867-2873.
  21. Li J, Raghunath M, Tan D.T.H, Lareu RR, Chen Z, Beuerman R.W. Defensins HNP1 and HBD2 stimulation of wound-associated responses in human conjunctival fibroblasts. Invest Ophthalmol Vis Sci 2006; 47(9):3811-3819.
  22. Lim L.S., Ho C.L., Ang L.P.K., Aung T., Tan D.T.H. Inferior corneal decompensation following laser peripheral iridotomy in the superior iris. Am J Ophthalmol 2006; 142(1):166-168.
  23. Liu S.H., Li J., Wang C.F., Tan D.T.H., Beuerman, R.W. Human limbal progenitor cell characterisitics are maintained in tissue culture. Ann Acad Med 2006; 35(2): 80 – 86
  24. Luo H.D., Gazzard G., Fong A., Aung T., Hoh S.T., Loon S.C., Healey P., Tan D.T.H., Wong T.Y., Saw S.M. Myopia, Axial Length, and OCT Characteristics of the Macula in Singaporean Children. Invest Ophthalmol Vis Sci 2006; 47(7):2773-2781.
  25. Luo H.D., Gazzard G., Liang Y., Shankar A., Tan D.T.H., Saw S.M . Defining myopia using refractive error and uncorrected logMAR visual acuity > 0.3 from 1334 Singapore school children ages 7-9 years. British Journal of Ophthalmology 2006;90[3]:362-366
  26. Saw S.M., Shankar A., Tan S.B., Taylor H., Tan D.T.H., Stone R.A., Wong T.Y. A cohort study of incident myopia in Singaporean children. Invest Ophthalmol Vis Sci 2006; 47(5):1839-1844.
  27. Tan DT, Ang LP. Modified automated lamellar therapeutic keratoplasty for keratoconus: a new technique. Cornea 2006; 25(10):1217-1219.
  28. Tan D.T.H. Donald Tan, MD, on neurovision, a non-optical approach to correcting the effects of refractive error. Refractive Eyecare 2006; 10(5):31-34.
  29. Tong L., Chan Y.H., Gazzard G., Tan D.T.H, Saw S.M. Longitudinal study of anisometropia in Singaporean school children. J Cataract Refrag Surg 2006 ; 47(8) : 3247 - 3252
  30. Vithana E.N., Morgan P., Sundaresan P., Ebenezer N.D., Tan D.T.H., Mohamed M.D., Anand S., Khine K.O., Venkataraman D., Yong V.H., Salto-Tellez M., Venkatraman A., Guo K., Hemadevi B., Srinivasan M., Prajna V., Khine M., Casey J.R., Inglehearn C.F., Aung T. Mutations in sodium-borate cotransporter SLC4A11 cause recessive congenital hereditary endothelial dystrophy (CHED2). Nat Genet 2006; 38(7):755-757.
  31. Wei R.H., Lim L., Chan W.K., Tan D.T.H . Evaluation of orbscan II corneal topography in individuals with myopia. Ophthalmology 2006;113[2]:177-183
  32. Wei R.H., Lim L., Chan W.K., Tan D.T.H . Higher order ocular aberrations in eyes with myopia in a Chinese population. 2005. J Refract Surg 2006; 22(7): 695-702
  33. Wong Y.W., ChewJ., Yang H., Tan D.T.H., Beuerman R.W. Expression of insulin-like growth factor binding protein- 3 in pterygium tissue. Br J Ophthalmol 2006 Jun; 90(6):769-772.
  34. Zhou L., Beuerman R.W., Foo Y.H., Liu S.P., Ang L.P.K., Tan D.T.H . Characterisation of human tear proteins using high-resolution mass spectrometry. Annals, Academy of Medicine, 2006; 35(6): 400 - 408
  35. Ang L.P.K., Tan D.T.H., Seah C.J.Y., Beuerman R.W. The use of Human Serum in Supporting the In Vitro and In Vivio Proliferation of Human. Br J Ophthalmol 2005; 89(6): 748 – 752
  36. Ang L.P.K., Tan D.T.H. Autologous Cultivated Conjunctival Transplantation for Recurrent Viral Papillomata. Am J Ophthalmol 2005; 140(1): 136 - 138
  37. Ang L.P.K., Tan D.T.H., Cajucom-Uy H., Phan T.T., Beuerman R.W . Autologous cultivated conjunctival transplatation for pterygium surgery. Am J Ophthalmol 2005; 139(4): 611 – 619
  38. Cheng C.L., Theng J.T., Tan D.T.H. Compressive C-shaped lamellar keratoplasty A surgical alternative for the management of severe astigmatism from peripheral corneal degeneration. Ophthalmology 2005;112[3]:425-430
  39. Chong Y.S., Liang Y., Tan D.T.H., Gazzard G., Stone R.A., Saw S.M . Association between breastfeeding and likelihood of myopia in children. JAMA 2005;293[24]:3001-3002
  40. Farook M., Venkatramani J., Gazzard G., Cheng A., Tan D.T.H., Saw S.M. Comparisons of the handheld autorefractor, table-mounted autorefractor, and subjective refraction in Singapore. Optom Vis Sci 2005;82[12]:1066-1070
  41. Husain R., Tong L., Fong A., Cheng J.F, How A., Chua W.H. Lee L., Gazzard G., Tan D.T.H., Koh D., Saw S.M. . Prevalence of cataract in rural Indonesia. Ophthalmology 2005;112[7]:1255-1262
  42. Luu C., Lau A., Koh A., Tan D.T.H. . Multifocal electroretinogram in children on atropine treatment for myopia. British Journal of Ophthalmology 2005;89[2]:151-153
  43. Rosman M, Wong T.Y., Koh C.L., Tan D.T.H. . Prevalence and causes of amblyopia in a population-based study of young adult men in Singapore. Am J Ophthalmol 2005; 140(3): 551 –552
  44. Saw S.M., Chua W.H., Gazzard G., Koh D., Tan D.T.H., Stone R.A . Eye growth changes in myopic children in Singapore. Br J Ophthalmol 2005;89[11]:1489-1494.
  45. Saw S.M., Tong L., Chua W.H., Chia K.S., Koh D., Tan D.T.H., Katz J. Incidence and progression of myopia in Singaporean school children. Invest Ophthalmol Vis 2005;46[1]:51-57.
  46. Tan D.T.H., Lam D.S., Chua W.H., Shu-Ping D.F., Crockett R.S . One-year multicenter, double-masked, placebo-controlled, parallel safety and efficacy study of 2% pirenzepine ophthalmic gel in children with myopia. Ophthalmology 2005;112[1]:84-91.
  47. Carkeet A., Saw S.M., Gazzard G., Tang W., Tan D.T.H . Repeatability of IOLMaster biometry in children. Optom Vis Sci 2004;81(11):829-834.
  48. Ang L.P.K., Tan D.T.H., Cajucom-Uy H., Phan T.T., Beuerman R.W., Lavker R.M. Reconstruction of the ocular surface by transplantation of a serum free cultivated conjunctival tissue equivalent. Ann Acad Med Singapore 2004;33(5 Suppl):S55-S56.
  49. Ang L.P.K., Tan D.T.H. Ocular surface stem cells and disease. Current conceptsand clinical applications. Ann Acad Med Singapore 2004;33(5):576-580.
  50. Saw S.M., Tong L., Chia K.S., Koh D., Lee Y.S., Katz J., Tan D.T.H. The relation between birth size and the results of refractive error and biometry measurement in children. Br J Ophthalmol 2004;88(4):538-542.
  51. Saw S.M., Chia K.S., Linstrom J.M., Tan D.T.H., Stone R.A. Childhood myopia and parental smoking. Br J Ophthalmol 2004;88(7):934-937.
  52. Shen W.Y., Lee S.Y., Yeo I., Lai C.M., Mathur R., Tan D.T.H., Constable I.J., Rackoczy P.E. Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey. Arch Ophthalmol 2004;122(3):353-360.
  53. Tong L., Tan D.T.H., Abano J.M., Lim L . Deep anterior lamellar keratoplasty in a patient with descemetocele following gonococcal keratitis. Am J Ophthalmol 2004;138(3):506-507.
  54. Tong L., Saw S.M, Lin Y., Chia K.S., Koh D., Tan D.T.H. Incidence and pregression of astigmation in Singaporean children. Invest Ophthalmol Vis Sci 2004. 45(11)3914-3918.
  55. Tong L., Saw S.M., Siak J.K., Gazzard G., Tan D.T.H. Corneal thickness determination and correlates in Singaporean Schoolchildren. Invest Ophthalmol Vis Sci 2004;45(11):4004-4009.
  56. Tong L., Saw S.M., Chan E.S., Yap M., Lee H.Y., Kwang Y.P., Tan D.T.H. . Screening for myopia and refractive errors using LogMAR visual acuity by optometristic and simplified visual acuity chart by nurses. Optom Vis Sci 2004;81(9):684-691.
  57. Tong L., Saw S.M., Chua W.H., Luu C., Cheng B., Yeo I., Wong E., Tan D.T.H., Koh A. Optic disk and retinal characteristics in myopic children. Am J Ophthalmol 2004;138(1):160-162
  58. Tan D.T.H., Ang L.P.K. Automated lamellar therapeutic keratoplasty for post-PRK corneal scarring and thinning. AM J Ophthalmol 2004;138[6]:1067-1609
  59. Chua W.H., Tan D.T.H., Chan W.K. Performance of the Hansatome microsuction ring for laser in situ keratomileusis in eyes with narrow palpebral apertures. J Cateract Refract Surg 2004;30[11]:2344-2348
  60. Ang L.P.K., Tan D.T.H., Phan T.T., Li J., Beuerman R., Lavker R.M . The in vitro and in vivo proliferative capacity of serum-free cultivated human conjunctival epithelial cells. Curr Eye Res 2004;28:307-317
  61. Ang L.P.K., Tan D.T.H., Beuerman R.W., Lavker R.M . Development of a Conjunctival Epithelial Equivalent with Improved Proliferative Properties Using a Multistep Serum-Free System. Investigative Ophthalmology & Visual Science 2004;45:1-7.
  62. Tan D.T.H. The Future is Near: Focus on Myopia. Singapore Medical Journal 2004;45:407-411.
  63. Saw S.M., Tan S.B., Fung D., Chia K.S., Koh D., Tan D.T., Stone R.A. . IQ and the association with myopia in children. Invest Ophthalmol Vis Sci 2004;45:2943-2948.
  64. Tan D.T.H., Ang L.P.K, Beuerman R.W . Reconstruction Of The Ocular Surface By Transplantation Of A Serum-Free Derived Cultivated Conjunctival Epithelial Equivalent. Transplantation 2004;77.
  65. Tong L., Saw S.M., Chia K.S., Tan D.T.H. Anisometropia in Singapore school children. Am J Ophthalmol 2004;137:474-479.
  66. Zhou L, Huang L.Q., Beuerman R.W., Grigg M., Li S.F.Y., Chew F.T., Ang L.P.K., Stern M.E., Tan D.T.H., `. Proteomic Analysis of Human Tears: Defensin Expression after Ocular Surface Surgery. Journal of Proteome Research 2004;410-416
  67. Lee A.J., Saw S.M., Gazzard G., Cheng A., and Tan D.T.H. Intraocular pressure associations with refractive error and axial length in children. Br.J.Ophthalmol. 88[1], 5-7.2004
  68. Sakoonwatanyoo P., Tan D.T.H., and Smith D.R. Expression of p63 in pterygium and normal conjunctiva. Cornea 23[1], 67-70.2004
  69. Chan C.M., Theng J.T., Lim L., and Tan, D.T.H. Microsporidial keratoconjunctivitis in healthy individuals: a case series. Ophthalmology 110[7], 1420-1425.2003
  70. Hicks C.R., Crawford G.J., Lou X., Tan D.T.H., Snibson G.R., Sutton G., Downie N., Werner L., Chirila T.V., and Constable I.J. Corneal replacement using a synthetic hydrogel cornea, AlphaCor trade mark : device, preliminary outcomes and complications. Eye 17[3], 385-392.2003
  71. Hicks C.R., Crawford G.J., Tan D.T.H., Snibson G.R., Sutton G.L., Downie N., Gondhowiardjo T.D., Lam D.S., Werner L., Apple D., and Constable I.J. AlphaCor cases: comparative outcomes. Cornea 22[7], 583-590.2003
  72. Lee K.Y., Gazzard G., and Tan D.T.H. Ciliary body arteriovenous malformation? Eye 17[5], 658-659.2003
  73. Lee S.Y., Chee S.P., Balakrishnan V., Farzavandi S., and Tan D.T.H. Surodex in paediatric cataract surgery. Br.J.Ophthalmol. 87[11], 1424-1426.2003
  74. Saw S.M., Husain R., Gazzard G.M., Koh D., Widjaja D., and Tan D.T.H. Causes of low vision and blindness in rural Indonesia. Br.J.Ophthalmol. 87[9], 1075-1078.2003
  75. Shen W.Y., Lee S.Y., Yeo Y.S.I., Lai C.M., Mathur R., Tan D.T.H., Constable I.J., and Rakoczy P. E. Predilection of the macular region to high incidence of choroidal neovascularization after intense laser photocoagulation in the monkey. Archives of Ophthalmology .2003
  76. Tan D.T.H. and Ang L.P.K. Stem cells of the eye: An illuminating viewpoint. Singapore Medical Association News 35[6], 7-9.2003
  77. Theng J.T., Ti S.E., Zhou L., Lam K.W., Chee S.P., and Tan D.T.H. Pharmacokinetic and toxicity study of an intraocular cyclosporine DDS in the anterior segment of rabbit eyes. Invest Ophthalmol.Vis.Sci. 44[11], 4895-4899.2003
  78. Ti S.E., and Tan D.T.H. Tectonic corneal lamellar grafting for severe scleral melting after pterygium surgery. Ophthalmology 110[6], 1126-1136.2003
  79. Wong T.Y., and Tan D.T.H. The SERI-ARVO Meeting and future challenges of ophthalmic research in Asia. Br.J.Ophthalmol. 87[4], 379-380.2003
  80. Zhou L., Beuerman R.W., Barathi A., and Tan D.T.H. Analysis of rabbit tear proteins by high-pressure liquid chromatography/electrospray ionization mass spectrometry. Rapid Commun.Mass Spectrom. 17[5], 401-412.2003
  81. Carkeet A., Luo H.D., Tong L., Saw S.M., and Tan D.T.H. Refractive error and monochromatic aberrations in Singaporean children. Vision Research 42[14], 1809-1824.2002
  82. Chan C.M.L., Liu Y.P., and Tan D.T.H. Ocular surface changes in pterygium. Cornea 21[1], 38-42.2002
  83. Crawford G.J., Hicks C.R., Lou X., Vijayasekaran S., Tan D.T.H., Mulholland B., Chirila T.V., and Constable I.J. The chirila keratoprosthesis: Phase-I human clinical trial. Ophthalmology 109[5], 883-889.2002
  84. Gazzard G., Saw S.M., Farook M., Koh D., Widjaja D., Chia S.E., Hong C.Y., and Tan D.T.H. Pterygium in Indonesia: Prevalence, severity and risk factors. British Journal of Ophthalmology 86[12], 1341-1346.2002
  85. Gazzard G.A., Saw, S.M., Koh D., Farook M., Widjaja D., Lee J., and Tan D.T.H. Refractive error in Sumatra, Indonesia - A population-based prevalence survey. Asia Pacific Biotech News 6[2], 49-50.1-21-2002
  86. Hicks C.R., Crawford G.J., Tan D.T.H., Snibson G. Sutton G.L., Gondhowiardjo T.D., Lam D.S., and Downie N. Outcomes of implantation of an artificial cornea, AlphaCor: Effects of prior ocular herpes simplex infection. Cornea 21[7], 685-690.2002
  87. Lee A.J., Lee J., Saw S.M., Gazzard G., Koh D., Widjaja D., and Tan D.T.H. Prevalence and risk factors associated with dry eye symptoms: A population based study in Indonesia. British Journal of Ophthalmology 86[12], 1347-1351.2002
  88. Looi A.L.G., Lim L., and Tan D.T.H. Visual rehabilitation with new-age rigid gas-permeable scleral contact lenses - A case series. Annals Academy of Medicine 31[2], 234-237.2002
  89. Saw S.M., Shih-Yen E.C., Koh A. H.C., and Tan D.T.H. Interventions to retard myopia progression in children: An evidence- based update. Ophthalmology 109[3], 415-421.2002
  90. Saw S.M., Gazzard G., Koh D., Farook M., Widjaja D., Lee J., and Tan D.T.H. Prevalence rates of refractive errors in Sumatra, Indonesia. Investigative Ophthalmology & Visual Science 43[10], 3174-3180.2002
  91. Saw S.M., Carkeet A., Chia K.S., Stone R.A., and Tan D.T.H. Component dependent risk factors for ocular parameters in Singapore Chinese children. Ophthalmology 109[11], 2065-2071.2002
  92. Saw S.M., Zhang M.Z., Hong R.Z., Fu Z.F., Pang M.H., and Tan D.T.H. Near-work activity, night-lights, and myopia in the Singapore-China study. Archives of Ophthalmology 120[5], 620-627.2002
  93. Saw S.M., Gazzard G., Au Eong K.G., and Tan D.T.H. Myopia: Attempts to arrest progression. British Journal of Ophthalmology 86[11], 1306-1311.2002
  94. Saw S.M., Tseng P., Chan W.K., Chan T.K., Ong S.G., and Tan D.T.H. Visual function and outcomes after cataract surgery in a Singapore population. Journal of Cataract Refractive Surgery 28[3], 445-453.2002
  95. Saw S.M., Chua W.H., Hong C.Y., Wu H.M., Chan W.Y., Chia K.S., Stone R.A., and Tan D.T.H. Nearwork in early-onset myopia. Investigative Ophthalmology & Visual Science 43[2], 332-339.2002
  96. Saw S.M., Chua W.H., Hong C.Y., Wu H.M., Chia K.S., Stone R.A., and Tan D.T.H. Height and its relationship to refraction and biometry parameters in Singapore Chinese children. Investigative Ophthalmology & Visual Science 43[5], 1408-1413.2002
  97. Tan D.T.H. Ocular surface disease in the Asia-Pacific. Asia Pacific Biotech News 6[2], 53-54.1-21-2002
  98. Tan D.T.H. and Foulds W.S. Research in ophthalmology and vision in the Asia-Pacific region: The Singapore Eye Research Institute Story. Asia Pacific Biotech News 6[2], 35-36.1-21-2002
  99. Theng J.T.S., Zhou L., Tan D.T.H., and La K.W. Distribution of cyclosporin A in the cornea after topical or oral administration. Journal of Ocular Pharmacology and Therapeutics 18[1], 83-88.2002
  100. Tong L., Saw S.M., Tan D.T.H., Chia K.S., Chan W.Y., Carkeet A., Chua W.H., and Hong C.Y. Sensitivity and specificity of visual acuity screening for refractive errors in school children. Optometry and Vision Science 79[10], 650-657.2002
  101. Tong L., Saw S.M., Carkeet A., Chan W.Y., Wu H.M., and Tan D.T.H. Prevalence rates and epidemiological risk factors for astigmatism in Singapore school children. Optometry and Vision Science 79[9], 606-613.2002
  102. Xiong X., Tan D.T.H., Barathi A., and Beuerman R.W . Assay of leucyl aminopeptidase activity invitro by high-performance liquid chromatography with fluorescence detection. Analytical Biochemistry .2002
  103. Au Eong K.G., Pieramici D.J., Fujii G.Y., Ng E.W., Humayun M.S., Maia M., Harlan J.B., Jr Schachat A.P., Beatty S., Toth C. A., Thomas M. A., Lewis H., Eckardt C., Tano Y., and de Juan E. Macular translocation: unifying concepts, terminology, and classification. American Journal of Ophthalmology 131[2], 244-253.2001
  104. Chan C.M.L., Chew P.T.K., Alsagoff Z., Wong J.S., and Tan D.T.H . Vascular patterns in pterygium and conjunctival autografting: A pilot study using indocyanine green anterior segment angiography. British Journal of Ophthalmology 85[3], 350-353.2001
  105. Cheng C.L., Chee S.P., and Tan D.T.H. Patient reliability in the administration of topical ocular medication. Singapore Medical Journal 42[6], 252-254.2001
  106. Lim L., Tan D.T.H., and Chan W.K. Therapeutic use of Bausch & Lomb PureVision contact lenses. The CLAO Journal 27[4], 179-185.2001
  107. Looi A.L.G., Gazzard G., and Tan D.T.H. Surgical exploration minimised by ultrasound biomicroscopy localisation of intraocular foreign body. Eye 15[Pt 2], 234-235.2001
  108. Saw S.M., Chan B., Seenyen L., Yap M., Tan D.T.H., and Chew S.J. Myopia in Singapore kindergarten children. Optometry 72[5], 286-291.2001
  109. Saw S.M., Hong C.Y., Chia K.S., Stone R.A., and Tan D.T.H. Nearwork and myopia in young children. Lancet 357[9253], 390.2001
  110. Saw S.M., Wu H.M., Hong C.Y., Chua W.H., Chia K.S., and Tan D.T.H. Myopia and night lighting in children in Singapore. British Journal of Ophthalmology 85[5], 527-528.2001
  111. Saw S.M., Hong R.Z., Zhang M.Z., Fu Z.F., Ye M., Tan D.T.H., and Chew S.J. Near-work activity and myopia in rural and urban schoolchildren in China. Journal of Pediatric Ophthalmology & Strabismus 38[3], 149-155.2001
  112. Scott A. and Tan D.T.H. Therapeutic lamellar keratoplasty for limbal dermoids. Ophthalmology 108[10], 1858-1867.2001
  113. Seet B., Wong T.Y., Tan D.T.H., Saw S.M., Balakrishnan V., Lee L.K., and Lim A. S. Myopia in Singapore: taking a public health approach. British Journal of Ophthalmology 85[5], 521-526.2001
  114. Tan D.T.H., Chee S.P., Lim L., Theng J., and Van Ede M. Randomized clinical trial of Surodex steroid drug delivery system for cataract surgery: anterior versus posterior placement of two Surodex in the eye. Ophthalmology 108[12], 2172-2181.2001
  115. Theng J.T.S., Lim W.K., Lee L., Tan D.T.H., and Chew S.J. Microbiological Profile of a Shipboard Environment and the Flora on Contact Lenses of Seamen. The CLAO Journal 27[1], 47-52.2001
  116. Theng J.T.S., Chan C., Ling M.L., and Tan D.T.H. Microsporidial keratoconjunctivitis in a healthy contact lens wearer without human immunodeficiency virus infection. Ophthalmology 108[5], 976-978.2001
  117. Ti S.E. and Tan D.T.H. Recurrent corneal erosion after laser in situ keratomileusis. Cornea 20[2], 156-158.2001
  118. Tong L., Carkeet A., Saw S.M., and Tan D.T.H. Corneal and refractive error astigmatism in Singaporean schoolchildren: a vector-based Javal's rule. Optometry and Vision Science 78[12], 881-887.2001
  119. Wong T.Y., Foster P.J., Johnson G.J., Seah S.K.L., and Tan D.T.H. The prevalence and risk factors for pterygium in an adult Chinese population in Singapore: the Tanjong Pagar survey. American Journal of Ophthalmology 131[2], 176-183.2001
  120. Xiong X., Lim B.A., Lat-Luna M., Chew P.T.K., and Tan D.T.H . Quantitation of mitomycin C in human ocular tissues by high-performance liquid chromatography-photo-diode array detection. Journal of Chromatography B 755[1-2], 65-72.2001
  121. Zhou L., Tan, D.T.H, Theng J.T.S., Lim L., Liu Y.P., and Lam K.W. Optimized analytical method for cyclosporin A by high-performance liquid chromatography-electrospray ionization mass spectrometry. Journal of Chromatography B 754[1], 201-207.2001
  122. Alsagoff Z., Tan D.T.H, and Chee S.P. Necrotising scleritis after bare sclera excision of pterygium. British Journal of Ophthalmology 84[9], 1050-1052.2000
  123. Khoo J., Saw S.M., Banerjee K., Chia S.E., and Tan D.T.H. Outdoor work and the risk of pterygia: a case-control study. International Ophthalmology 22[5], 293-298.2000
  124. Lee S.B., Li D.Q., Tan D.T., Meller D.C., and Tseng S.C. Suppression of TGF-beta signaling in both normal conjunctival fibroblasts and pterygial body fibroblasts by amniotic membrane. Current Eye Research 20[4], 325-334.2000
  125. Lim L., Siow K.L., Sakamoto R., Chong J.S.C., and Tan D.T.H . Reverse geometry contact lens wear after photorefractive keratectomy, radial keratotomy, or penetrating keratoplasty. Cornea 19[(3)], 320-324.2000
  126. Saw S.M., Banerjee K., and Tan D.T.H. Risk factors for the development of pterygium in Singapore: A hospital-based case-control study. Acta Ophthalmologica Scandinavica 78, 216-220.2000
  127. Tan D.T.H . Who's afraid of prevention of blindness? British Journal of Ophthalmology 84, 943-944.2000
  128. Tan D.T.H, Liu Y.P., and Sun L. . Flow cytometry measurements of DNA content in primary and recurrent pterygia. Investigative Ophthalmology & Visual Science 41[7], 1684-1686.2000
  129. Tan D.T.H., Tang W.Y., Liu Y.P., Goh H.S., and Smith D.R. Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium. British Journal of Ophthalmology 84[2], 212-216.2000
  130. Ti S.E., Chee S.P., Dear K.B.G., and Tan D.T.H . Analysis of variation in success rates in conjunctival autografting for primary and recurrent pterygium. British Journal of Ophthalmology 84, 385-389.2000
  131. Wang Z.J., Ma S.A., Pan J.C., Zhou L., Tan D.T.H, and Lam K.W. The identification of uric acid as the major reducing agent on normal corneal surface. Hong Kong Journal of Ophthalmology 3[2], 15-17.2000
  132. Yip C.C., Tan D.T.H., Balakrishnan V., and Choo C.T. High-pressure paint gun injury to the orbit and ocular adnexa. International Ophthalmology 22[6], 335-339.2000
  133. Chee S.P., Ti S.E., Sivakumar M., and Tan D.T.H. Postoperative inflammation: extracapsular cataract extraction versus phacoemulsification. Journal of Cataract Refractive Surgery 25[September], 1280-1285.1999
  134. Cheng C.L. and Tan D.T.H. Lamellar corneal autograft for corneal perforation. Australian and New Zealand Journal of Ophthalmology 27, 437-439.1999
  135. Ho C.L., Tan D.T.H., and Chan W.K. Excimer laser phototherapeutic keratectomy for recurrent corneal erosions. Annals Academy of Medicine 28.6[November], 787-790.1999
  136. Jap A., Chan C., Lim L., and Tan D.T.H. Conjunctival rotation autograft for pterygium. An alternative to conjunctival autografting. Ophthalmology 106[1], 67-71.1999
  137. Lee S.Y. and Tan D.T.H. Changing trends in cataract surgery in Singapore. Singapore Medical Journal 40.4, 256-259.1999
  138. Lim L., Siow K.L., Chong J.S.C., and Tan D.T.H. Contact lens wear after photorefractive keratectomy: comparison between rigid gas permeable and soft contact lenses. The CLAO Journal 25.4[October], 222-227.1999
  139. Pires R.T.F., Tseng S.C.G., Prabhasawat P., Puangsricharern V., Maskin S.L., Kim J.C., and Tan D.T.H. Amniotic membrane transplantation for symptomatic bullous keratopathy. Archives of Ophthalmology 117[October], 1291-1297.1999
  140. Saw S.M. and Tan D.T.H. Pterygium: prevalence, demography and risk factors. Ophthalmic Epidemiology 6.2.1999
  141. Tan D.T.H., Chee S.P., Lim L., and Lim A. S. Randomized clinical trial of a new dexamethasone delivery system (Surodex) for treatment of post-cataract surgery inflammation. Ophthalmology 106[2], 223-231.1999
  142. Tan D.T.H. Conjunctival grafting for ocular surface disease. Current Opinion in Ophthalmology 10[4], 277-281.1999
  143. Wee T.L., Chan W.K., Tseng P., Tan D.T.H., Balakrishnan V., and Low C.H. Excimer laser photorefractive keratectomy for the correction of myopia. Singapore Medical Journal 40[4], 246-250.1999
  144. Fong K.S., Balakrishnan V., Chee S.P., and Tan D.T.H. Refractive change following pterygium surgery. The CLAO Journal 24.2[April], 115-117.1998
  145. Liew G.C., Au F., Ku J., Tan P.H., Cheah E., and Seah L.L. Unusual presentation of a mammoth globe-differential diagnoses and management. Asia Pacific Journal of Ophthalmology 10.3[July], 26-29.1998
  146. Tan D.T.H., Chee S.P, Dear K.B.G., and Lim A.S.M. Efecto de la morfologia del pterigium en la recurrencia del mismo en un estudio controlado comparando autoinjerto conjunctival con escision simple de esclera. Archives of Ophthalmology 9.2[March-April].1998.
  147. Chan C.M.L., Wong T.Y., Yeong S.M., Lim T.H., and Tan D.T.H. Penetrating keratoplasty in the Singapore National Eye Centre and donor cornea acquisition in the Singapore Eye Bank. Annals Academy of Medicine 26.4[July], 395-400.1997
  148. Chew S.J., Choo C.T., Seah L.L., Tan J. and Cheng H.M. . High-resolution MRI of the eye. Asia-Pacific Journal of Ophthalmology 9[1], 2-5.1997
  149. Lim L., Ng T.P., and Tan D.T.H. Accurate intraocular pressure measurement in contact lens wearers with normal pressures. The CLAO Journal 23.2[April], 130-133.1997
  150. Ong W.C. and Tan, D.T.H. Successful penetrating keratoplasty after conjunctival flap surgery for herpetic stromal necrosis. Asia Pacific Journal of Ophthalmology 9.1[January], 25-28.1997
  151. Sivakumar M. and Tan D.T.H. Descemetocele following a simple avulsion procedure for pterygium. British Journal of Ophthalmology 81.3, 253-254.1997
  152. Tan D.T.H., Lim A.S.M., Goh H.S, and Smith, D.R. Abnormal expression of the p53 tumor suppressor gene in the conjunctiva of patients with pterygium. American Journal of Ophthalmology 123.3[March], 404-405.1997
  153. Tan D.T.H., Chee S,P., Dear, K,B.G., and Lim A.S.M. Effect of pterygium morphology on pterygium recurrence in a controlled trial comparing conjunctival autografting with bare sclera excision. Archives of Ophthalmology 115[October], 1235-1240.1997
  154. Theng J.T.S. and Tan D.T.H. Combined penetrating keratoplasty and limbal allograft transplantation for severe corneal burns. Ophthalmic Surgery and Lasers 28.9[September], 765-768.1997
  155. Wong D.W.K., Chan W.K., and Tan D.T.H. Harvesting a lamellar graft from a corneoscleral button: A new technique. American Journal of Ophthalmology 123.5[May], 688-689.1997
  156. Wong J.S., Balakrishnan V., and Tan K.L . Spontaneous corneal perforation in premature infants. Singapore Medical Journal 38.11, 469-470.1997
  157. Wong T.Y., Chan C.M.L., Lim L., Lim T.H., and Tan D.T.H. Changing indications for penetrating keratoplasty: A newly developed country's experience. Australian and New Zealand Journal of Ophthalmology 25, 145-150.1997
  158. Wong T.Y., Ng T.P., Fong K.S., and Tan D.T.H. Risk factors and clinical outcomes between fungal and bacterial keratitis: A comparative study. The CLAO Journal 23.4[October], 275-281.1997
  159. Wong T.Y., Fong K.S., and Tan D.T.H. Clinical and microbial spectrum of fungal keratitis in Singapore: A 5-year retrospective study. International Ophthalmology 21, 127-130.1997
  160. Yip C.C., Lim L., and Tan D.T.H. The surgical management of an advanced pterygium involving the entire cornea. Cornea 16.3, 365-368.1997
  161. Chng N.W., Tan D.T.H., and Chee S.P. Case of surgically-induced necrotizing scleritis. Asia Pacific Journal of Ophthalmology 8.3[July], 31-32.1996
  162. Fong K.S., Tan D.T.H., Chee S.P., and Seah S.K.L. Successful trabeculectomy with 5-fluorouracil after pterygium excision with conjunctival autograft - A case report. Asia Pacific Journal of Ophthalmology 8.4[October], 32-34.1996
  163. Quah B.L., Wong E.Y.M., Tseng P.S.F., Low C.H., and Tan D.T.H. Analysis of photorefractive keratectomy patients who have not had PRK in their second eye. Ophthalmic Surgery and Lasers 27.5[May], S429-S434.1996
  164. Siow K.L., Chan W.K., Low C.H., and Tan D.T.H. Problems of refraction after photorefractive keratectomy. Journal of the American Optometric Association 67.12[December], 755-761.1996
  165. Tan D.T.H., Ficker L.A., and Buckley R.J. Limbal transplantation. Ophthalmology 103.1[January], 29-36.1996
  166. Lee S.Y. and Tan D.T.H. Bilateral mooren's ulcers treated with lamellar corneoscleral keratoplasty. Asia Pacific Journal of Ophthalmology 7.3[July], 27-31.1995
  167. Lim W.K., Yip C.C., Fong K.S., and Tan D.T.H . Positive Siedel's test five months after surgery. Asia Pacific Journal of Ophthalmology 7.3[July], 25-26.1995
  168. Tan D.T.H., Pullum K.W., and Buckley R.J. Medical applications of scleral contact lenses: 1. A retrospective analysis of 343 cases. Cornea 14.2, 121-129.1995
  169. Tan D.T.H., Lee C.P.L., and Lim A.S.M. Corneal ulcers in two institutions in Singapore: Analysis of causative factors, organisms and antibiotic resistance. Annals Academy of Medicine 24.6[November], 823-829.1995
  170. Tan D.T.H., Pullum K.W., and Buckley R.J. Medical applications of scleral contact lenses: 2. Gas-permeable scleral contact lenses. Cornea 14.2, 130-137.1995
  171. Chan T.K., Tan D.T.H., Yeoh R.L.S., Low C.H., and Lim A.S.M. Introduction to phacoemulsification - A controlled entry. Asia Pacific Journal of Ophthalmology 6.3[July], 6-11.1994
  172. Wong S., Chan T.K., Tan D.T.H., and Low, C.H. Post-phacoemulsification aspergillus endophthalmitis: A case report. Asia Pacific Journal of Ophthalmology 6.4[October], 31-34.1994
  173. Wong T.Y. and Tan D.T.H. Ocular rosacea with salzmannoid degeneration. Asia Pacific Journal of Ophthalmology 6.4[October], 35-37.1994
  174. Balakrishnan V., Lim A.S.M., Low C.H., Lee C.P., Tseng P.S.F., Chan W.K., Chan T.K., Tan J., and Tan D.T.H. Excimer laser photorefractive keratectomy in Singapore - A new treatment modality for myopia. Singapore Medical Journal 34, 309-312.1993
  175. Lim T.H., Tan D.T.H., and Fu E.R.Y. Advanced cataract in Singapore - Its prognosis and complications. Annals Academy of Medicine 22.6[November], 891-894.1993
  176. Ong S.G., Heng L.K., Tan B.B.H., Ang C.L., and Ang B.C. Perfluorocarbon liquids (Perfluorodecalin) in vitreoretinal surgery - A local experience. Annals Academy of Medicine 22.3[May], 348-350.1993
  177. Tan D.T.H., Fu E.R.Y., Lim T.H., and Fan R.F.T. A retrospective study of cataract surgery in the Singapore General Hospital in 1990. Annals Academy of Medicine 22.6[November], 885-890.1993
  178. Tan D.T.H. and Chee S.P . Early central posterior capsular fibrosis in sulcus-fixated biconvex intraocular lenses. Journal of Cataract Refractive Surgery 19[July], 471-480.1993
  179. Tan D.T.H. Morning glory syndrome with exercise-induced amaurosis fugax. Asia Pacific Journal of Ophthalmology 5.1[January], 16-18.1993
  180. Balakrishnan V., Lim A.S.M., Low C.H., Lee C.P., Tseng P.S.F., Chan W.K., Chan T.K., Tan J., and Tan D.T.H. Excimer laser photorefractive keratectomy in Singapore - A preliminary report. Asia Pacific Journal of Ophthalmology 4.4[October], 2-7.1992
  181. Tan D.T.H. Neodymium: Yag laser zonulysis in ectopia lentis - A case report. Asia Pacific Journal of Ophthalmology 4.3[July], 29-31.1992
  182. Tseng P.S.F., Tan D.T.H., and Yong V.S.H. Singapore General Hospital's experience in corneal grafting. Annals Academy of Medicine 20.4[July], 429-432.1991
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